Activities
Stem Cells from Adipose Tissue
Mesencell Biotech GmbH headquarter are based in Switzerland with research and production laboratories in several countries around the world.
Mesencell Biotech activities include:
1. Installation of biotech laboratories
► ¨Evaluation of URS (user requirement specification), infrastructure and location
► Purveyance of equipment, media and consumables
► IQ/OQ/PQ: installation / operational and performance qualification
► Creation of GLP and GMP (good laboratory practice, good manufacturing practice) documentation
► Education and continuing education of personnel
► Hands-on help with manufacturing in the first weeks
2. Production within biotech laboratories
► Periodic verification of equipment, processes and personnel
► Half yearly and yearly audits
►Continuing education of personnel
► CAPA (corrective action preventive action)
► Creation of objectives and management by objectives
3. Research facilities / laboratories
►Management of international research
►Management of research facilities and research personnel
►Establishment of research projects and their management
►Collaboration between research units and research and extra muros partners and production laboratories
► Hands-on research in one or all of the laboratories in key research areas such as olfactory ensheathing cells, den dritic cells, insulin producing cells and dopamine producing cells
4. Clinical studies
► Creation of clinical investigator’s brochures and case report forms in key study areas such as Antimorbidity, os teoarthritis, cardiovascular diseases, spinal cord injuries, Anticancer, diabetes, Parkinson disease and Alzheimer disease
► Clinical monitoring of studies
► Coordination of study centres and clinicians
► Interpretation of studies including statistical analysis
► Publications
► Lectures
► Drug regulatory affairs
5. Preclinical in vitro studies
► Evaluation of new medication or chemicals on cartilage explant model and cell lines regarding possible damaging properties or regenerative /antinflammatory/antiapoptic properties
► Evaluation of glucose and oxygen deprivation in cardiomyocytes
► Testing of anti-inflammatory effects of dendrittic cells and mesenchymal stem cells on skin models
► Differentiation of mesenchymal stem cells (MSC) into Insulin producing cells (IPC)
► Differentiation of mesenchymal cells into Dopamine producing cells (DPC)
► Testing of possible tumourigenicity of MSCs, IPCs and DPCs with the soft agar colony forming assay